Our laboratory explores the regulation of cell renewal, tissue remodelling and the acquisition of specific cell fates in a spatio-temporal order during organogenesis. We focus on the development of the inner ear to understand the signals and cellular events that lead to the senses of hearing and balance. Which signals allow the precise pattern of sensory neurons and hair cells, are those re-used during regeneration, how is patterning coupled with morphogenesis for a functional organ and how epithelia are organized? 

Lately we have focused on imaging cell behaviours and the communication signals during otic neurogenesis to undestand deafenss and neuropathies.

The lab combines high resolution imaging technologies with genetic, pharmacological and mechanical perturbations in zebrafish.

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